The Weldon School of Biomedical Engineering at Purdue University covers five areas of research which include Engineered Biomaterials and Tissue Systems, Biophotonics and Medical Imaging, Systems Science and Engineering, Neuroengineering, and Orthopaedic Biomechanics. The research performed at the Weldon School of Biomedical Engineering focuses on improving worldwide healthcare.
This series contains publications from the Weldon School of Biomedical Engineering at Purdue University.
Submissions from 2023
Method for estimating pulsatile wall shear stress from one-dimensional velocity waveforms, J.C. Muskat, Charles F. Babbs, C.J. Goergen, and V.L. Rayz
Transport of nitrite from large arteries modulates regional blood flow during stress and exercise, Joseph C. Muskat, Charles F. Babbs, Craig J. Goergen, and Vitaliy L. Rayz
Submissions from 2022
Rapid Assembly of A Polar Network Architecture Drives Efficient Actomyosin Contractility, Vlad Costache, Serena Prigent Garcia, Camille N. Plancke, Jing Li, Simon Begnaud, Shashi Kumar Suman, Anne-Cecile Reymann, Taeyoon Kim, and Francois B. Robin
Myocardial Strain Imaging in Duchenne Muscular Dystrophy, Conner C. Earl, Jonathan Soslow, Larry W. Markham, and Craig J. Goergen
Heart rate and age modulate retinal pulsatile patterns, Ivana Labounková, René Labounek, Radim Kolář, Ralf P. Tornow, Charles F. Babbs, Collin M. McClelland, Benjamin R. Miller, and Igor Nestrašil
Estimating external tissue support parameters with fluid-structure interaction models from 4D ultrasound of murine thoracic aortae, Tanmay C. Shidhore, Hannah L. Cebull, Megan C. Madden, Ivan C. Christov, Vitaliy L. Rayz, and Craig J. Goergen
A Two-Phase Approach to Re-calibrating Expensive Computer Simulation for Sex-Specific Colorectal Neoplasia Development Modeling, Carolina Vivas-Valencia, You Zhou, Aditya Sai, Thomas F. Imperiale, and Nan Kong
Submissions from 2020
Fully Dried Two-Dimensional Paper Network for Enzymatically Enhanced Detection of Nucleic Acid Amplicons, Kristin M. Byers, Anna R. Bird, HyunDae D. Cho, and Jacqueline C. Linnes
Submissions from 2019
Stone Skipping Physics, Charles F. Babbs
Ex Vivo Electrochemical Measurement of Glutamate Release During Spinal Cord Injury, James K. Nolan, Tran N. H. Nguyen, Mara Fattah, Jessica C. Page, Riyi Shi, and Hyowon Lee
Submissions from 2017
An Automated Workflow for Quantifying RNA Transcripts in Individual Cells in Large Data-sets, Matthew C. Pharris, Tzu-Ching Wu, Xinping Chen, Xu Wang, David M. Umulis, Vikki M. Weake, and Tamara L. Kinzer-Ursem
Submissions from 2016
A potential new technique to estimate the origins of focal atrial tachycardias from 12-lead electrocardiograms, Charles F. Babbs
Dispersion Curve Engineering of TiO2/Silver Hybrid Substrates for Enhanced Surface Plasmon Resonance Detection, Sherif H. El-Gohary, Munsik Choi, Young L. Kim, and Kyung Min Byun
Environment and Its Influence on Health and Demographics in South Korea, Ramiro D. Bravo Santisteban, Young L. Kim, Umar Farooq, Tae-Seong Kim, Sekyoung Youm, and Seung-Hun Park
Submissions from 2015
The origin of Korotkoff sounds and the accuracy of auscultatory blood pressure measurements, Charles F. Babbs
Optimizing strategies for population-based chlamydia infection screening among young women: An age-structured system dynamics approach Infectious Disease epidemiology, Yu Teng, Nan Kong, and Wanzhu Tu
Submissions from 2014
A compact theory of magnetic nerve stimulation: predicting how to aim, Charles F. Babbs
Choosing inclusion criteria that minimize the time and cost of clinical trials, Charles F. Babbs
Noninvasive measurement of cardiac stroke volume using pulse wave velocity and aortic dimensions: a simulation study, Charles F. Babbs
Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation, Chang Kim, Jeongho Park, and Myunghoo Kim
Ontogenetic Scaling Patterns and Functional Anatomy of the Pelvic Limb Musculature in Emus (Dromaius novaehollandiae), Luis P. Lamas, Russell P. Main, and John R. Hutchinson
Model-Based Analysis for Qualitative Data: An Application in Drosophila Germline Stem Cell Regulation., Michael S. Pargett, Ann E. Rundell, Gregery T. Buzzard, and David Michael Umulis
Physical Weight Loading Induces Expression of Tryptophan Hydroxylase 2 in the Brain Stem., Joon W. Shim, Todd R. Dodge, Max A. Hammond, Joseph M. Wallace, Feng C. Zhou, and Hiroki Yokota
Estimating Age-Dependent Per-Encounter Chlamydia Trachomatis Acquisition Risk Via a Markov-Based State-Transition Model., Yu Teng, Nan Kong, and Wanzhu Tu
Submissions from 2013
Flow Measurements in a Blood-Perfused Collagen Vessel Using X-Ray Micro-Particle Image Velocimetry., Elizabeth Antoine, Cara Buchanan, Kamel Fezzaa, Wah-Keat Lee, Nichole Rylander, and Pavlos Vlachos
The Case for Interposed Abdominal Compression CPR in Hospital Settings, Charles F. Babbs
We still need a real-time hemodynamic monitor for CPR, Charles F. Babbs
Subtle Paranodal Injury Slows Impulse Conduction in a Mathematical Model of Myelinated Axons., Charles F. Babbs and Riyi Shi
Submissions from 2012
Optimizing Electrode Placement for Hemodynamic Benefit in Cardiac Resynchronization Therapy, Charles F. Babbs
Oscillometric Measurement of Systolic and Diastolic Blood Pressures Validated in a Physiologic Mathematical Model, Charles F. Babbs
Predicting success or failure of immunotherapy for cancer: insights from a clinically applicable mathematical model, Charles F. Babbs
No-Shows to Primary Care Appointments: Subsequent Acute Care Utilization among Diabetic Patients, Lynn A. Nuti, Mark Lawley, Ayten Turkcan, Lingsong Zhang, Karen Chang, Deanna R. Willis, and Laura P. Sands
Differential Mitochondrial Toxicity Screening and Multi- Parametric Data Analysis, Maria V. Tsiper, Jennifer Sturgis, Larisa V. Avramova, Shilpa Parakh, Raymond Fatig, Ana Juan-García, Nianyu Li, Bartek Rajwa, Padma Narayanan, C. W. Wualls Jr., Joseph P. Robinson, and Vincent J. Davisson
Submissions from 2011
Quantitative Reappraisal of the Helmholtz-Guyton Resonance Theory of Frequency Tuning in the Cochlea, Charles F. Babbs
Real-Time CARS Imaging Reveals a Calpain-Dependent Pathway for Paranodal Myelin Retraction during High-Frequency Stimulation., Terry B. Huff, Yunzhou Shi, Wenjing Sun, Wei Wu, Riyi Shi, and Ji-Xin Cheng
Submissions from 2010
Anterior-posterior impedance cardiography: a new approach to accurate, non-invasive monitoring of cardiac function, Charles F. Babbs
Behavior of a Viscoelastic Valveless Pump: a Simple Theory with Experimental Validation, Charles F. Babbs
An Optimal Control Theory Approach to Non-Pharmaceutical Interventions, Feng Lin, Kumar Muthuraman, and Mark Lawley
Sensor to Detect Endothelialization on an Active Coronary Stent, Katherine M. Musick, Arthur C. Coffey, and Pedro P. Irazoqui Dr.
A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis elegans Using Label and Label-Free Methods., Kelvin Yen, Thuc T. Le, Ankita Bansal, Sri Devi Narasimhan, Ji-Xin Cheng, and Heidi A. Tissenbaum
Submissions from 2009
Quantitative prediction of body surface potentials from myocardial action potentials using a summed dipole model, Charles F. Babbs
Neonatal CPR: room at the top—a mathematical study of optimal chest compression frequency versus body size, Charles F. Babbs, Andrew Meyer, and Vinay Nadkarni
Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction., Yan Fu, Wenjing Sun, Yunzhou Shi, Riyi Shi, and Ji-Xin Cheng
Single-Cell Profiling Reveals the Origin of Phenotypic Variability in Adipogenesis., Thuc T. Le and Ji-Xin Cheng
Coherent Anti-Stokes Raman Scattering Imaging of Lipids in Cancer Metastasis., Thuc T. Le, Terry B. Huff, and Ji-Xin Cheng
Methods for Calculating Coronary Perfusion Pressure During CPR, Michael P. Otlewski, Leslie A. Geddes, Michael Pargett, and Charles F. Babbs
Submissions from 2008
A New Paradigm for Human Resuscitation Research Using Intelligent Devices, Charles F. Babbs, Andre E. Kemeny, Weilun Quan, and Gary Freeman
SBML-SAT: a Systems Biology Markup Language (SBML) Based Sensitivity Analysis Tool, Zhike Zi, Yanan Zheng, Ann E. Rundell, and Edda Klipp
Submissions from 2007
Statistical analysis of joint short-term and long-term survival in resuscitation research, Charles F. Babbs
Submissions from 2006
A new biomechanical head injury criterion, Charles F. Babbs
Design of near-optimal waveforms for chest and abdominal compression and decompression in CPR using computer-simulated evolution, Charles F. Babbs
A novel open field activity detector to determine spatial and temporal movement of laboratory animals after injury and disease, Andrew O. Koob, John Cirillo, and Charles F. Babbs
Submissions from 2005
Biophysics of cardiopulmonary resuscitation with periodic z-axis acceleration of abdominal compression at aortic resonant frequencies, Charles F. Babbs
Effects of an impedance threshold valve upon hemodynamics in standard CPR: studies in a refined computational model, Charles F. Babbs
Relative effectiveness of interposed abdominal compression CPR: sensitivity analysis and recommended compression rates, Charles F. Babbs
A dose-response curve for the negative bias pressure of an intrathoracic pressure regulator during CPR, Charles F. Babbs and Demetris Yannopoulos
Optimal Control Theory Applied to a Difference Equation Model of Cardiopulmonary Resuscitation, Eunok Jung, Charles F. Babbs, Suzanne Lenhart, and Vladimir A. Protopoescu
Intravenous Polyethylene Glycol Inhibits the Loss of Cerebral Cells after Brain Injury, Andrew O. Koob, Bradley S. Duerstock, Charles F. Babbs, Yinlong Sun, and Richard B. Borgens
Submissions from 2004
Brain motion and deformation during closed head injury in the presence of cerebrospinal fluid, Charles F. Babbs
Meta-analysis of Two-Treatment Clinical Trials Including Both Continuous and Dichotomous Results, Charles F. Babbs
Optimizing Chest Compression to Rescue Ventilation Ratios During One-Rescuer CPR by Professionals and Lay Persons: Children are Not Just Little Adults, Charles F. Babbs and Vinay Nadkarni
Optimization of Ectopic Gene Expression in Skeletal Muscle Through DNA Transfer by Electroporation., Jordan Taylor, Charles F. Babbs, Mohammed Borhan Alzghoul, Aaron Olsen, Mickey Latour, Amber L. Pond, and Kevin Hannon
Submissions from 2003
Interposed Abdominal Compression CPR: A Comprehensive Evidence Based Review, Charles F. Babbs
Simplified Meta-analysis of Clinical Trials in Resuscitation, Charles F. Babbs
Submissions from 2002
Circulatory Adjuncts: Newer Methods of Cardiopulmonary Resuscitation, Charles F. Babbs
Optimum Compression to Ventilation Ratios in CPR Under Realistic, Practical Conditions: a physiological and mathematical analysis, Charles F. Babbs and Karl B. Kern
Submissions from 2001
Biomechanics of Heading a Soccer Ball: Implications for Player Safety, Charles F. Babbs
Consensus evidence evaluation in resuscitation research: analysis of Type I and Type II errors, Charles F. Babbs
Submissions from 2000
Submissions from 1999
Mechanics of CPR Performed with the Patient on a Soft Bed Versus a Hard Surface, John M. Boe and Charles F. Babbs
Submissions from 1998
Multiresolution detection of spiculated lesions in digital mammograms, Sheng Liu, Charles F. Babbs, and Edward Delp
Submissions from 1995
Theoretically Optimal Duty Cycles for Chest and Abdominal Compression during External Cardiopulmonary Resuscitation, Charles F. Babbs and Keir Thelander
Preliminary Results of Deferoxamine and L1 Treatment of Spinal Cord Ischemia, David G. Reuter, Willis A. Tacker Jr, Charles F. Babbs, Stephen F. Badylak, William D. Voorhees, and Peter E. Konrad
Submissions from 1994
The Evolution of Abdominal Compression in Cardiopulmonary Resuscitation, Charles F. Babbs
Interposed abdominal compression as an adjunct to cardiopulmonary resuscitation, Charles F. Babbs, Jeffrey B. Sack, and Karl B. Kern
Submissions from 1993
Interposed abdominal compression cardiopulmonary resuscitation: Are we missing the mark in clinical trials?, Charles F. Babbs
Interposed Abdominal Compression-CPR: A Case Study in Cardiac Arrest Research, Charles F. Babbs
Pre-Clinical ROC Studies of Digital Stereomammography, Jean Hsu, Charles F. Babbs, David M. Chelberg, Zygmunt Pizlo, and Edward J. Delp
Development of a rapidly computable descriptor of prostate tissue temperature during transurethral conductive heat therapy for benign prostate hyperplasia, U H. Patel and Charles F. Babbs
Submissions from 1992
Oxygen Radicals in Ulcerative Colitis, Charles F. Babbs
Histochemical demonstration of endothelial superoxide and hydrogen peroxide generation in ischemic and reoxygenated rat tissues, Charles F. Babbs, Meloney D. Cregor, and Stephen F. Badylak
Evidence of changes in regional blood perfusion in human intracranial tumours during conductive interstitial hyperthermia, U H. Patel, Charles F. Babbs, J A. DeFord, W M. Bleyer, J A. Marchosky, and C J. Moran
A Computer-Based, Automated, Telephonic System to Monitor Patient Progress in the Home Setting, Umesh H. Patel and Charles F. Babbs
Submissions from 1991
Endothelial Superoxide Production in the Isolated Rat Heart During Early Reperfusion After Ischemia -- A Histochemical Study, Charles F. Babbs, Meloney D. Cregor, John J. Turek, and Stephen F. Badylak
Effective Estimation and Computer Control of Minimum Tumour Temperature During Conductive Interstitial Hyperthermia, J A. DeFord, Charles F. Babbs, U H. Patel, M W. Bleyer, J A. Marchosky, and C J. Moran
Design and evaluation of closed-loop feedback control of minimum temperatures in human intracranial tumors treated with interstitial hyperthermia, J A. Deford, Charles F. Babbs, U H. Patel, N E. Fearnot, J A. Marchosky, and C J. Moran
Methylene Blue as an Inhibitor of Superoxide Generation by Xanthene Oxidase: A Potential New Drug for the Attenuation of Ischemia/Reperfusion Injury, Steven C. Salaris, Charles F. Babbs, and William D. Voorhees
Submissions from 1990
Free radicals and the etiology of colon cancer, Charles F. Babbs
A Pressure sensitive Mat for Measuring Contact pressure Distributions of Patients Lying on Hospital Beds, Charles F. Babbs, Joe D. Bourland, George P. Graber, James T. Jones, and William E. Schoenlein
Theoretical Basis for Controlling Minimal Tumor Temperature During Interstitial Conductive Heat Therapy, Charles F. Babbs, Neal E. Fearnot, J A. Marchosky, C J. Moran, James T. Jones, and T D. Plantenga
Simulation of Free Radical Reactions in Biology and Medicine: A New Two-Compartment Kinetic Model of Intracellular Lipid Peroxidation, Charles F. Babbs and Melissa Gale Steiner
Accuracy and precision of computer-simulated tissue temperatures in individual human intracranial tumours treated with interstitial hyperthermia, J A. DeFord, Charles F. Babbs, U H. Patel, N E. Fearnot, J A. Marchosky, and C J. Moran
Quantitation of the Hydroxyl Radical by Reaction with Dimethyl Sulfoxide, Melissa G. Steiner and Charles F. Babbs
Submissions from 1989
Scatchard Analysis of Methane Sulfinic Acid Production from Dimethyl Sulfoxide: A Method to Quantify Hydroxyl Radical Formation in Physiologic Systems, Charles F. Babbs and David W. Griffin
Lethal Hydroxyl Radical Production in Paraquat-treated Plants, Charles F. Babbs, Jo Ann Pham, and Ronald C. Coolbaugh
Changes in Expired End-Tidal Carbon Dioxide During Cardiopulmonary Resuscitation in Dogs: A Prognostic Guide for Resuscitation Efforts, Karl B. Kern, Arthur B. Sanders, William D. Voorhees, Charles F. Babbs, Willis A. Tacker, and Gordon A. Ewy
Effect of Oxygen Concentration on the Formation of Malondialdehyde-Like Material in a Model of Tissue Ischemia and Reoxygenation, Steven C. Salaris and Charles F. Babbs
Quantitative Effects of Iron Chelators on Hydroxyl Radical Production by the Superoxide-Driven Fenton Raction, Jean Blair Smith, Joanne C. Cusumano, and Charles F. Babbs
Submissions from 1988
Myocardial Perfusion Pressure: A Predictor of 24Hour Survival During Prolonged Cardiac Arrest in Dogs, Karl B. Kern, Gordon A. Ewy, William D. Voorhees, Charles F. Babbs, and Willis A. Tacker
A Rapid, Widely Applicable Screen for Drugs that Suppress Free Radical Formation in Ischemia/Reperfusion, Steven C. Salaris and Charles F. Babbs