The mechanical property and behavior of the lipid membrane is ubiquitously relevant to cellular processes. Studies in these areas find wide applications in cellular biophysics, pathology, and bio-inspired engineering. Recent work focuses on exploring membrane response via deformation-based assays, including a variety of techniques such as optic tweezing, micro-pipetting, electrodeformation, and flow-based deformation. In this minisymposium, we aim to bring together forefront research in both vesicle and cell mechanics. The former, which is a self-enclosed lipid membrane or liposome, is often employed as a model system to explore salient and relevant features and functionalities. The presentations will discuss recent progresses to understand the challenging mechanical problems that involve fluid-structure interactions and/or how these results can be applied to engineering applications. Importantly, this forum attempts to catalyze interactions between the vesicle and cell research communities: the former has frequently a strong focus on the simple yet fundamental physical aspects, whereas the later are often from a proper biological/pathological perspective.

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Schedule

Biological cells adhesion mediated by receptors–ligands binding

Ben Nadler, University of Victoria

Cell uptake of one-dimensional nanomaterials

Xin Yi, Brown University, United States

Coupling the vesicle dynamics to a transmembrane inclusion

Yuan Young, New Jersey Institute of Technology

Electric-field-driven deformation, poration, and phase separation in biomimetic membranes

Petia Vlahovska, Brown University, United States

Electroporation dynamics of giant lipid vesicles

Karin Riske, Universidade de Sao Paulo, Brazil
Rafael Lira, Universidade de Sao Paulo, Brazil
Rumiana Dimova, Max Planck Institute of Colloids and Interfaces, Germany

Mechanics and physics of HIV virus interaction with cell membranes

Himani Agrawal, University of Houston, United States
Matthew Zelisko, University of Houston, United States
Pradeep Sharma, University of Houston, United States

Ralaxation of deformed drops, vesicles, and cells

Miao Yu, Rutgers University, United States
Hao Lin, Rutgers University, United States
Rafael Lira, Universidade de Sao Paulo, Brazil
Karin Riske, Universidade de Sao Paulo, Brazil
Rumiana Dimova, Max Planck Institute of Colloids and Interfaces, Germany

Shape transitions of vesicles in linear, hyperbolic flows: asymmetric dumbbells, pearling, and buckling

Vivek Narsimhan, Stanford University, United States
Andrew Span, Stanford University, United States
Eric Shaqfeh, Stanford University, United States

Study of surface configuration of soft spherical shell under cylindrical indenters

Sina Youssefian, Worcester Polytechnic Institute, United States
Nima Rahbar, Worcester Polytechnic Institute, United States

Tension induced growth in cells

Prashant Purohit, University of Pennsylvania

The minimum electrical field that can be detected by a biological membrane—thermal noise limit

Fatemeh Ahmadpoor, University of Houston, United States
Pradeep Sharma, University of Houston, United States
Liping Liu, Rutgers University, United States

Theoretical study of biological membrane response to temperature gradients at the single cell level

Lior Atia, Technion, Israel
Sefi Givli, Technion, Israel