Abstract
Cells are the fundamental building block of complex tissues in higher-order organisms. These cells take different forms and shapes to perform a broad range of functions. What makes a cell uniquely eligible to perform a task, however, is not well-understood; neither is the defining characteristic that groups similar cells together to constitute a cell type. Even for known cell types, underlying pathways that mediate cell type-specific functionality are not readily available. These functions, in turn, contribute to cell type-specific susceptibility in various disorders.
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Computer Science
Date of Award
January 2016
Recommended Citation
Mohammadi, Shahin, "Cell Type-specific Analysis of Human Interactome and Transcriptome" (2016). Open Access Dissertations. 1371.
https://docs.lib.purdue.edu/open_access_dissertations/1371
First Advisor
Ananth Grama
Second Advisor
Wojciech Szpankowski
Committee Member 1
David Gleich
Committee Member 2
Jennifer Neville
Committee Member 3
Markus Lill