Date of Award

January 2015

Degree Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Department

Mechanical Engineering

First Advisor

Eugenio Culurciello

Second Advisor

George T.C. Chiu

Committee Member 1

Da-Ting Lin

Committee Member 2

Justin Seipel

Abstract

The brain is the most complex and least understood biological system known to man. New imaging techniques are providing scientists with an entirely new perspec- tive on the study of the functional brain at a neural circuit level, enabling in-depth understanding of both physiological processes and animal models of neurological and psychiatric diseases which currently lack e↵ective treatments. These new tools come at the cost of meeting the challenges associated with the miniaturization of the hard- ware for in vivo recordings

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