Abstract
Understanding the immune system and its responses to foreign threats (antigens) is a matter of understanding the immune cells involved, their individual responses, and chemicals responsible for intracellular and intercellular communication. The overall immune response is driven by individual actions of neutrophils, antigen-presenting cells, and lymphocytes (T cells and B cells), among other cells. Intercellular communication is the means by which immune cells develop coordinated response while intracellular signals determine responses within a cell; both depend on systems of chemical reactions at their respective scales. The perspective taken in this dissertation is that of understanding B cells at the intracellular scale and the signaling molecules responsible for its responses.
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Mathematics
Date of Award
January 2015
Recommended Citation
McGee, Reginald, "MODELING, ANALYSIS, AND CONTROL OF SYK-MEDIATED SIGNALING EVENTS FOR B CELLS AND ASSOCIATED CELLULAR RESPONSE FOR B CELLS" (2015). Open Access Dissertations. 1312.
https://docs.lib.purdue.edu/open_access_dissertations/1312
First Advisor
Gregery T Buzzard
Committee Member 1
Ann E Rundell
Committee Member 2
Robert L Geahlen
Committee Member 3
Zhilan Feng