Abstract
In eukaryotes, there are highly coupled mechanisms that require RNA-binding proteins to facilitate gene expression. Proper RNA structure and ribonucleoprotein (RNP) complex formation are critical for gene expression. DEAD-box proteins are the largest class of RNA helicases that play fundamental roles in RNA and RNP structure remodeling. However, the precise biological role of the vast majority of the ~ 40 members in this family has not been completely described. Therefore, my research focused on characterizing the role of the DEAD-box RNA helicase Dbp2 during gene expression in S. cerevisiae.
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Biochemistry
Date of Award
January 2015
Recommended Citation
Ma, Wai Kit, "CHARACTERIZATION OF THE FUNCTION OF THE DEAD-BOX RNA HELICASE DBP2" (2015). Open Access Dissertations. 1127.
https://docs.lib.purdue.edu/open_access_dissertations/1127
First Advisor
Elizabeth J Tran
Committee Member 1
Barbara L Golden
Committee Member 2
Mark C Hall
Committee Member 3
Robert L Geahlen