Date of Award
January 2015
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Biochemistry
First Advisor
Elizabeth J Tran
Committee Member 1
Barbara L Golden
Committee Member 2
Mark C Hall
Committee Member 3
Robert L Geahlen
Abstract
In eukaryotes, there are highly coupled mechanisms that require RNA-binding proteins to facilitate gene expression. Proper RNA structure and ribonucleoprotein (RNP) complex formation are critical for gene expression. DEAD-box proteins are the largest class of RNA helicases that play fundamental roles in RNA and RNP structure remodeling. However, the precise biological role of the vast majority of the ~ 40 members in this family has not been completely described. Therefore, my research focused on characterizing the role of the DEAD-box RNA helicase Dbp2 during gene expression in S. cerevisiae.
Recommended Citation
Ma, Wai Kit, "CHARACTERIZATION OF THE FUNCTION OF THE DEAD-BOX RNA HELICASE DBP2" (2015). Open Access Dissertations. 1127.
https://docs.lib.purdue.edu/open_access_dissertations/1127