Surface immobilizable chelator for label-free electrical detection of pyrophosphate

Author

• David J. Liu, Intel Corp., Santa Clara, CA
• Grace M. Credo, Intel Corp., Santa Clara, CA
• Xing Su, Intel Corp., Santa Clara, CA
• Kai Wu, Intel Corp., Santa Clara, CA
• Hsiao C. Lim, Intel Corp., Santa Clara, CA
• Oguz H. Elibol, Purdue University
• Rashid Bashir, University of Illinois at Urbana-Champaign
• Madoo Varma, Intel Corp., Santa Clara, CA

Abstract

A new pyrophosphate (PPi) chelator was designed for surface-sensitive electrical detection of biomolecular reactions. This article describes the synthesis of the PPi-selective receptor, its surface immobilization and application to label-free electrical detection on a silicon-based field-effect transistor (FET) sensor.

DOI

10.1039/c1cc12073e

Citation

Chem. Commun., 2011,47, 8310-8312 DOI: 10.1039/C1CC12073E

Date of this Version

2011

Recommended Citation

Liu, David J.; Credo, Grace M.; Su, Xing; Wu, Kai; Lim, Hsiao C.; Elibol, Oguz H.; Bashir, Rashid; and Varma, Madoo, "Surface immobilizable chelator for label-free electrical detection of pyrophosphate" (2011). Birck and NCN Publications. Paper 772.
http://dx.doi.org/10.1039/c1cc12073e