SERS aptasensor from nanorod-nanoparticle junction for protein detection
Abstract
A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.
Keywords
ENHANCED RAMAN-SCATTERING; THROMBIN DETECTION; SILVER ELECTRODE; GOLD NANORODS; DNA DETECTION; APTAMER; SPECTROSCOPY; PROBES; CANCER; IMMUNOASSAY
Date of this Version
2010
Recommended Citation
Wang, Yuling; Lee, Kyuwan; and Irudayaraj, Joseph, "SERS aptasensor from nanorod-nanoparticle junction for protein detection" (2010). Birck and NCN Publications. Paper 631.
https://docs.lib.purdue.edu/nanopub/631
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