SERS aptasensor from nanorod-nanoparticle junction for protein detection
Date of this Version
2010This document has been peer-reviewed.
Abstract
A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.
Discipline(s)
Engineering | Nanoscience and Nanotechnology
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