Multifunctional calcium carbonate microparticles: Synthesis and biological applications
Abstract
Multifunctional composites based on calcium carbonate (CaCO3) spherical microparticles stabilized through the embedding of CdSe/ZnS/SiO2 nanoparticles into surface pores were fabricated. The stabilization of the vaterite polymorph of CaCO3 through nanoparticles embedding was necessary to generate a spherical, porous morphology of the microparticles. The CdSe/ZnS quantum dots were obtained and dispersed in aqueous solution after coating them with a silica shell via a reverse microemulsion approach. Green and red-emitting CaCO3-CdSe/ZnS/SiO2 microcomposites were analyzed via confocal laser-scanning fluorescence microscopy were to demonstrate their potential for imaging applications. The acetylcholinesterase (AChE) enzyme was immobilized into the pores of the spherical CaCO3-CdSe/ZnS/SiO2 microcomposites and the resulting hybrid material was used as a platform for the design of a pesticide biosensor. The detection limit for the paraoxon pesticide in aqueous solutions was determined to be of 4.6 nM.
Keywords
POROUS CACO3 MICROPARTICLES; QUANTUM DOTS; IN-VIVO; VATERITE; NANOPARTICLES; ENCAPSULATION; BIOSENSOR; SILICA; SENSOR; ORGANOPHOSPHORUS
Date of this Version
8-2010
Recommended Citation
Won, Yu-Ho; Jang, Ho Seong; Chung, Ding-Wen; and Stanciu, L, "Multifunctional calcium carbonate microparticles: Synthesis and biological applications" (2010). Birck and NCN Publications. Paper 622.
https://docs.lib.purdue.edu/nanopub/622