Gold Nanorod/Fe3O4 Nanoparticle "Nano-Pearl-Necklaces" for Simultaneous Targeting, Dual-Mode Imaging, and Photothermal Ablation of Cancer Cells

Chungang Wang, Purdue University - Main Campus
Jiji Chen, Purdue University - Main Campus
Tom Talavage, Purdue University - Main Campus
Joseph Irudayaraj, human breast cancer cells (SK-BR-3 cells). Birck Nanotechnology, Bindley Bioscience, and Purdue Cancer Center, Purdue University

Abstract

The combination of nanomaterials with different properties (such as magnetization, fluorescence, and near-infrared absorption) into one single object of nanoscale dimensions can lead to the development of multifunctional nanomedical platforms for simultaneous targeting, imaging, and therapy administration. Of the various kinds of nanoparticles available, magnetic nanoparticles (MNPs) have been utilized as versatile probes in biomedical applications, because of their utility in magnetic resonance imaging (MRI).

Discipline(s)

Biomedical Engineering and Bioengineering | Nanoscience and Nanotechnology