Nanoparticles for multimodal in vivo imaging in nanomedicine
Date of this Version
2014Abstract
While nanoparticles are usually designed for targeted drug delivery, they can also simultaneously provide diagnostic information by a variety of in vivo imaging methods. These diagnostic capabilities make use of specific properties of nanoparticle core materials. Near-infrared fluorescent probes provide optical detection of cells targeted by real-time nanoparticle-distribution studies within the organ compartments of live, anesthetized animals. By combining different imaging modalities, we can start with deep-body imaging by magnetic resonance imaging or computed tomography, and by using optical imaging, get down to the resolution required for real-time fluorescence-guided surgery.
Discipline(s)
Nanoscience and Nanotechnology
Comments
This is the Publisher PDF of Key, J and Leary, JF. "Nanoparticles for multimodal in vivo imaging in nnomedicine." International Journal of Nanomedicine, 9(1):711-726. 2014. Published by Dove Press, it is made available here with a CC-BY-NC license and is also available at http://dx.doi.org/10.2147/IJN.S53717.