Selective Weighing of Individual Microparticles Using a Hybrid Micromanipulator-Nanomechanical Resonator System
Abstract
We report a system based on a combination of a micromanipulator and a cantilever-based differential resonator for selecting and weighing individual micro-scale particles. Instead of relying on probabilistic attachment of particles on sensor surfaces, the system can specifically select and weigh individual micro-entities. The micromanipulator is able to move particles from a native media to the surface of a resonator that can weigh particles with pg-level resolution. The system allows individually manipulating and weighing a wide variety of entities that can be visualized under a microscope, ranging from cell spheres to spore clusters and single diatom algae.
Keywords
Cantilever; resonator; micro-manipulator; diffraction; stem cell sphere; spore; diatom; STEM-CELLS; DIATOMS; SENSOR; MASS; BIOSENSOR; READOUT
DOI
10.1109/JSEN.2013.2262269
Date of this Version
8-2013
Recommended Citation
Chan, Bin-Da; Icoz, Kutay; Gieseck, Richard L.; and Savran, Cagri A., "Selective Weighing of Individual Microparticles Using a Hybrid Micromanipulator-Nanomechanical Resonator System" (2013). Birck and NCN Publications. Paper 1436.
http://dx.doi.org/10.1109/JSEN.2013.2262269