Maize Flavan-4-ols and Anthocyanins Alleviated Dextran Sulfate Sodium-Induced Colitis in Mice via Intestinal Barrier Function Restoration

Authors

Binning Wu, The Pennsylvania State University
Shiyu Li, Purdue University
Haotian Chang, Purdue University
Ruth Anderson, Purdue University
Surinder Chopra, The Pennsylvania State University
Lavanya Reddivari, Purdue UniversityFollow

Abstract

This study investigated the anti-inflammatory effects of anthocyanins and flavan-4-ols (precursor of phlobaphenes) within a whole-food matrix against dextran sulfate sodium (DSS)-induced colitis using four maize near-isogenic lines (NILs) that differ only in a single class of flavonoids. The four NILs are A (lacks anthocyanins and phlobaphenes), B (phlobaphenes +), C (anthocyanins +) and D (anthocyanins + and phlobaphenes +).

Comments

This is the publisher's version of Binning Wu, Shiyu Li, Haotian Chang, Ruth Anderson, Surinder Chopra, Lavanya Reddivari, Maize Flavan-4-ols and Anthocyanins Alleviated Dextran Sulfate Sodium-Induced Colitis in Mice via Intestinal Barrier Function Restoration, Current Developments in Nutrition, Volume 4, Issue Supplement_2, June 2020, Page 488, https://doi.org/10.1093/cdn/nzaa045_121

Date of this Version

5-29-2020

DOI

10.1093/cdn/nzaa045_121

Recommended Citation

Binning Wu, Shiyu Li, Haotian Chang, Ruth Anderson, Surinder Chopra, Lavanya Reddivari, Maize Flavan-4-ols and Anthocyanins Alleviated Dextran Sulfate Sodium-Induced Colitis in Mice via Intestinal Barrier Function Restoration, Current Developments in Nutrition, Volume 4, Issue Supplement_2, June 2020, Page 488, https://doi.org/10.1093/cdn/nzaa045_121