Airway carbon dioxide monitoring as a guide to the efficacy of cardiopulmonary resuscitation
Abstract
The objective of this research was to examine the relationship between airway CO$\sb2$ excretion and the efficacy of CPR. This was accomplished in two parts. In part one we examined CO$\sb2$ excretion and its relationship to CPR efficacy as defined by cardiac output, blood pressure and blood gases. A significant positive relationship was found between CO$\sb2$ excretion and cardiac output, as well as significant yet less strong relationship with arterial blood pressure. The blood gases did not present a clear picture, although arterial P$\sb{\rm CO\sb2}$ tended to be followed directly, and venous P$\sb{\rm O\sb2}$ inversely, by CO$\sb2$ excretion. The second part of the study extended the use of airway CO$\sb2$ excretion to determine if it could be used to predict survival from CPR. This was accomplished by examining the relationships between CO$\sb2$ excretion and regional blood flows and survival, in addition to cardiac output and blood pressure. Airway CO$\sb2$ excretion levels greater than 7.0 milliliters of CO$\sb2$ per minute per kilogram of body weight were associated with survival in 83% of the cases, while below 7.0 there was only 30% survival. Airway CO$\sb2$ excretion appears to correlate better with myocardial and cerebral blood flows than with any other regional blood flows. Survival was closely correlated with CO$\sb2$ excretion in this study. Regional blood flows significant to survival also correlated well with CO$\sb2$ excretion. Therefore, monitoring of airway CO$\sb2$ excretion provides an appropriate method of assessing CPR efficacy.
Degree
Ph.D.
Advisors
Voorhees, Purdue University.
Subject Area
Anatomy & physiology|Animals|Surgery
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