TWO LOCUS HAPLOID POPULATIONS WITH UNEQUAL RECOMBINATION RATES (GENETICS, SELECTION, FREQUENCIES)
Abstract
Haploid populations include organisms such as bacteria and viruses. Recombination is important in the immune responses of viruses and antibiotic resistance in bacteria. Equal recombination rates between two loci is quite plausible for diploid organisms, but it is not clear why this should hold for bacterial recombination. We study the effects of unequal recombination rates first in a determinate model which describes the haplotype frequencies. We show the long run behavior of the haplotype frequencies under various values of selection coefficients. Next, we study a stochastic model related to the deterministic one. We give conditions which will give the population a "high" probability of exponential growth.
Degree
Ph.D.
Subject Area
Statistics
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