Imaging of near-infrared fluorescence, absorption, and scatter in turbid media
Abstract
A nonlinear, Bayesian optimization scheme is presented for reconstructing fluorescent yield and lifetime, the absorption coefficient, and the diffusion coefficient in turbid media, such as biological tissue. The method utilizes measurements at both the excitation and emission wavelengths for reconstructing all unknown parameters. The effectiveness of the reconstruction algorithm is demonstrated by simulation and by application to experimental data from a tissue phantom containing the fluorescent agent indocyanine green.
Degree
Ph.D.
Advisors
Webb, Purdue University.
Subject Area
Biomedical research|Electrical engineering
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