"Datasets on The Genomic Positions of The MLL1 Morphemes, The ZFP57 Bin" by Minou Bina, Phillip Wyss et al.
 

Abstract

While MLL1 activates gene expression in most tissues, ZFP57 represses transcription. MLL1 selectively interacts with a group of nonmethylated DNA sequences known as the MLL1 morphemes. ZFP57 associates with a methylated hexamer (ZFBS), dispersed in the genomic DNA segments known as Imprinted Control Regions (ICRs) and germline Differentially Methylated Regions (gDMRs), to maintain allele-specific gene repression. We have identified a set of composite DNA elements (ZFBS-Morph overlaps) that provides the sequence context of ZFBS in the canonical ICRs/gDMRs. This report provides tables listing the nucleotide sequences of the MLL1 morphemes and ZFBS-Morph overlaps. The report also offers links to the data repository at Purdue University, for downloading the positions of the MLL1 morphemes, the ZFP57 binding site, and the ZFBS-Morph overlaps in the mouse genome.

Comments

This is the publishers version of Bina, Minou & Wyss, Phillip & Song, Xiaohui. (2017). Datasets on the genomic positions of the MLL1 morphemes, the ZFP57 binding site, and ZFBS-Morph overlaps in the build mm9 of the mouse genome. Data in Brief. 13. 10.1016/j.dib.2017.05.050.

Keywords

CpG-rich motifs, gene regulation, genomic imprinting, KMT2AMLL1 morphemes, mouse genome, ZFP57 binding site

Date of this Version

5-28-2017

DOI

10.1016/j.dib.2017.05.050

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