A promising therapy for ventricular fibrillation--a life-threatening cardiac arrhythmia--is the implantation of an automatic defibrillator. A critical component of such a device is the system that detects the presence of ventricular fibrillation. Automatic systems for detecting ventricular fibrillation have been tested with arrhythmias produced by electric shocks in normal canine hearts, but have not been tested with spontaneous arrhythmias in hyperirritable hearts. We have developed an animal model to create arrhythmias without electrical stimulation and have used it to test our automatic defibrillator. This model permits evaluation of both reliability to diagnose ventricular fibrillation and reliability to reject other tachyarrhythmias.
animal testing; automatic defibrillator; strophanthidin-toxic hearts; tachyarrhythmias; ventricular fibrillation detection
Date of this Version
Bourland, J D.; Babbs, Charles F.; Tacker, W A.; and Geddes, L A., "An animal model for testing automatic defibrillators" (1980). Weldon School of Biomedical Engineering Faculty Publications. Paper 99.