We have developed a method for measurement of cardiac output during CPR with ventricular fibrillation. The method avoids the problems encountered when conventional techniques are used under the conditions of very low cardiac output. The method consists of injecting 5% saline as the indicator into the left ventricle and detecting its appearance in the descending aorta by withdrawing blood through an electrically calibrated conductivity cell. The adequacy of indicator mixing has been verified by obtaining dilutions curves simultaneously from the brachial and femoral arteries. Cardiac output can be determined even when output is as low as 7 ml/min/kg during CPR with ventricular fibrillation. Repeated determinations can be made as often as every minute. This method offers promise as a practical research tool which can be used with dye indicators also.
Date of this Version
Geddes, L A. and Babbs, Charles F., "A New Technique for Repeated Measurement of Cardiac Output During Cardiopulmonary Resuscitation" (1980). Weldon School of Biomedical Engineering Faculty Publications. Paper 35.