Fourier-domain digital holographic optical coherence imaging of living tissue
Published in:
Applied Optics 46,22 (2007) 4999-5008;
Link to original published article:
http://dx.doi.org/10.1364/AO.46.004999
Abstract
Digital holographic optical coherence imaging is a full-frame coherence-gated imaging approach that uses a CCD camera to record and reconstruct digital holograms from living tissue. Recording digital holograms at the optical Fourier plane has advantages for diffuse targets compared with Fresnel off-axis digital holography. A digital hologram captured at the Fourier plane requires only a 2D fast Fourier transform for numerical reconstruction. We have applied this technique for the depth-resolved imaging of rat osteogenic tumor multicellular spheroids and acquired cross-section images of the anterior segment and the retinal region of a mouse eye. A penetration depth of 1.4 mm for the tumor spheroids was achieved. (c) 2007 Optical Society of America.
Keywords
Optics
Date of this Version
1-1-2007