Date of Award
January 2015
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Philip S Low
Committee Member 1
Christine A Hrycyna
Committee Member 2
David H Thompson
Abstract
Bacterial siderophores are a class of small organic compounds that are produced endogenously by bacteria to chelate essential ferric iron from their surroundings. Because the bioavailability of ferric iron is extremely low is physiological pH, the host of a parasitic infection can be a poor source of soluble Fe3+. Consequently, bacteria rely upon siderophore transport systems to efficiently scavenge the nutrient. Nearly every bacterial
Recommended Citation
Jarvis, Gregory Gene, "Chemical Synthesis of Bacterial Siderophores and Applications in Pathogen Detection" (2015). Open Access Theses. 1110.
https://docs.lib.purdue.edu/open_access_theses/1110