Abstract
High shear wet granulation is a particle design process used to increase the size of a primary powder material through the addition of liquid binder. This thesis focuses on the multi-scale nature of high-shear granulation in order to understand behavior changes due to coupled consolidation and coalescence as well as operational changes that occur during the scale up of horizontal ploughshare mixer granulators. The methodology relied on a micro-scale model for coalescence, a meso-scale model to describe flow within the granulator and a macro-scale population balance to describe the whole system.
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Chemical Engineering
Date of Award
January 2015
Recommended Citation
Pohlman, Daniel A., "MULTI-SCALE MODELING OF HIGH-SHEAR GRANULATION" (2015). Open Access Dissertations. 1424.
https://docs.lib.purdue.edu/open_access_dissertations/1424
First Advisor
James D Litster
Committee Member 1
Zoltan K Nagy
Committee Member 2
Carl R Wassgren
Committee Member 3
Gintaras V Reklaitis