Date of Award

January 2015

Degree Type


Degree Name

Doctor of Philosophy (PhD)


Animal Science

First Advisor

Mathew G. Alan

Second Advisor

Paul D. Ebner

Committee Member 1

Haley F. Oliver

Committee Member 2

Marcos H. Rostagno


Phage therapy is a promising antibacterial intervention that has received renewed interest in recent years. In this study, the antibacterial efficacy of phage treatments was tested in different food matrices, under different conditions, as well as in both phage cocktail and single phage forms. Additionally, this study also examined phage genome sequences, bacterial phage resistance, and the impact of orally administered phages on acute immune response and gut microbiome of the host in effort to more clearly assess the safety and long-lasting efficacy of phage-based treatments.