Laser-treated hydrophobic paper: an inexpensive microfluidic platform

Girish Chitnis, Purdue University
Zhenwen Ding, Purdue University - Main Campus
Chun-Li Chang, Purdue University - Main Campus
Cagri A. Savran, Birck Nanotechnology Center and School of Mechanical Engineering, Purdue University
Babak Ziaie, Birck Nanotechnology Center, Purdue University

Date of this Version



Lab Chip, 2011,11, 1161-1165


We report a method for fabricating inexpensive microfluidic platforms on paper using laser treatment. Any paper with a hydrophobic surface coating (e. g., parchment paper, wax paper, palette paper) can be used for this purpose. We were able to selectively modify the surface structure and property (hydrophobic to hydrophilic) of several such papers using a CO(2) laser. We created patterns down to a minimum feature size of 62 +/- 1 mu m. The modified surface exhibited a highly porous structure which helped to trap/localize chemical and biological aqueous reagents for analysis. The treated surfaces were stable over time and were used to self-assemble arrays of aqueous droplets. Furthermore, we selectively deposited silica microparticles on patterned areas to allow lateral diffusion from one end of a channel to the other. Finally, we demonstrated the applicability of this platform to perform chemical reactions using luminol-based hemoglobin detection.


Nanoscience and Nanotechnology