Peptide Nucleic Acid (PNA) Assemblies

Felice Butler, Purdue University
Tim Husk, Purdue University
Pei-Sze Ng, Purdue University
Donald E. Bergstrom, Birck Nanotechnology Center and Bindley Bioscience Center, Purdue University

Document Type Article

Poster for 2008 BNC Research Review


PNA is a synthetic DNA analog that contains the nucleic acid bases adenine, cytosine, guanine, and thymine on a neutral peptide-like backbone. LNA (locked nucleic acid) is a synthetic DNA analog in which the 2’-oxygen is linked to the 4’-carbon via a methylene unit, rendering the monomer more conformationally stable than that of DNA.