Abstract
Many epidemiological studies suggest an association between antibiotic exposure and the development of inflammatory bowel disease [IBD]. However, the majority of these studies are observational and still the question remains, “Does the specific antibiotic administration regimen play a role in the development of colitis?” This study aimed to compare the possible effects of continuous and intermittent antibiotic exposure on the development of colitis using a colitis-susceptible IL-10 knockout [IL-10–/–] mouse model.
Date of this Version
12-7-2021
DOI
10.1016/j.biopha.2021.112486
Recommended Citation
Shiyu Li, Yusong Jin, Wenyi Fu, Abigail D. Cox, Dale Lee, Lavanya Reddivari, Intermittent antibiotic treatment accelerated the development of colitis in IL-10 knockout mice, Biomedicine & Pharmacotherapy, Volume 146, 2022, 112486, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2021.112486.
Comments
This is the publisher's version of
Shiyu Li, Yusong Jin, Wenyi Fu, Abigail D. Cox, Dale Lee, Lavanya Reddivari, Intermittent antibiotic treatment accelerated the development of colitis in IL-10 knockout mice, Biomedicine & Pharmacotherapy, Volume 146, 2022, 112486, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2021.112486.