The Department of Comparative Pathobiology at Purdue University provides knowledge in disease phenomena basic to all species including humans, at the molecular, cellular, organismal and ecosystem level. Faculty, staff, and students are involved in research and learning in a variety of areas including pathobiology, infectious diseases and vaccines, cancer biology, nanomedicine, toxicology, disease surveillance and human-animal interactions.
This series contains publications from the Department of Comparative Pathobiology at Purdue University.
Submissions from 2022
Photosystem stoichiometry adjustment is a photoreceptor-mediated process in Arabidopsis, Iskander M. Ibrahim, Steven D. McKenzie, Jae Chung, Uma K. Aryal, Walter D. Leon-Salas, and Sujith Puthiyaveetil
Submissions from 2018
Physiological and behavioral effects of animal-assisted interventions for therapy dogs in pediatric oncology settings, Amy McCullough, Molly Jenkins, Ashleigh Ruehrdanz, Mary Jo Gilmer, Janice Olson, Anjali Pawar, Leslie Holley, Shirley Sierra-Rivera, Deborah E. Linder, Danielle Pinchette, Neil J. Grossman, Cynthia Hellman, Noémie Guérin, and Marguerite O'Haire
Submissions from 2016
In vitro antibacterial activity of rhodanine derivatives against pathogenic clinical isolates, Ahmed Abdelkhalek, Charles R. Ashby Jr., Bhargav A. Patel, Tanaji T. Talele, and Mohamed Naguieb Seleem
Ureaplasma diversum Genome Provides New Insights about the Interaction of the Surface Molecules of This Bacterium with the Host, Lucas M. Marques, Izadora S. Rezende, Maysa S. Barbosa, Ana M. Guimarães, Hellen B. Martins, Guilherme B. Campos, Naila C. do Nascimento, Andrea P. dos Santos, Aline T. Amorim, Verena M. Santos, Sávio T. Farias, Fernanda A C Carrence, Lauro M. de Souza, Melissa Buzinhani, Victor E. Arana-Chavez, Maria E. Zenteno, Gustavo P. Amarante-Mendes, Joanne Messick, and Jorge Timenetsky
Submissions from 2015
Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine, Tiebing Liang, Mouhamad Alloosh, Lauren N. Bell, Allison Fullenkamp, Romil Saxena, William G. Van Alstine, Phelan Bybee, Klára Werling, Michael Sturek, Naga Chalasani, and Howard C. Masuoka
Antibacterial evaluation of synthetic thiazole compounds in vitro and in vivo in a methicillin-resistant staphylococcus aureus (MRSA) skin infection mouse model, Haroon Mohammad, Mark A. Cushman, and Mohamed Naguieb Seleem
Antibacterial Characterization of Novel Synthetic Thiazole Compounds against Methicillin-Resistant Staphylococcus pseudintermedius, Haroon Mohammad, P.V. N. Reddy, Dennis Monteleone, Abdelrahman S. Mayhoub, Mark S. Cushman, G. Kenitra Hammac, and Mohamed N. Seleem
Repurposing Celecoxib as a Topical Antimicrobial Agent, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem
Repurposing clinical molecule ebselen to combat drug resistant pathogens, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem
Repurposing ebselen for Treatment of Multidrug-Resistant Staphylococcal Infections, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem
Submissions from 2014
Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation, Chang Kim, Jeongho Park, and Myunghoo Kim
Antibacterial Activity of Novel Cationic Peptides against Clinical Isolates of Multi-Drug Resistant Staphylococcus pseudintermedius from Infected Dogs, Mohamed F. Mohamed, G. Kenitra Hammac, Lynn F. Guptil, and Mohamed N. Seleem
Efficacy of Short Novel Antimicrobial and Anti-Inflammatory Peptides in a Mouse Model of Methicillin-Resistant Staphylococcus aureus (MRSA) Skin Infection, Mohamed F. Mohamed and Mohamed N. Seleem
Sorting Reality from What We Think We Know About Breast Cancer in Africa, Sulma I. Mohammed and Joe B. Harford
Chronic Proliferative Dermatitis in Sharpin Null Mice: Development of an Autoinflammatory Disease in the Absence of B and T Lymphocytes and IL4/IL13 Signaling., Christopher S. Potter, Zhe Wang, Kathleen A. Silva, Victoria E. Kennedy, Timothy M. Stearns, Lisa Burzenski, Leonard D. Shultz, Harm HogenEsch, and John P. Sundberg
Submissions from 2013
Energy Reallocation to Breeding Performance through Improved Nest Building in Laboratory Mice., Brianna N. Gaskill, Kathleen R. Pritchett-Corning, Christopher J. Gordon, Edmond A. Pajor, Jeffrey R. Lucas, Jerry K. Davis, and Joseph P. Garner
Social Behaviors Increase in Children with Autism in the Presence of Animals Compared to Toys., Marguerite E. O'Haire, Samantha J. McKenzie, Alan M. Beck, and Virginia Slughter
LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells., Selinda J. Orr, Ashley R. Burg, Tim Chan, Laura Quigley, Gareth W. Jones, Jill W. Ford, Deborah Hodge, Catherine Razzook, Joseph Sarhan, Yava L. Jones-Hall, Gillian C. Whittaker, Kimberly C. Boelte, Lyudmila Lyakh, Marco Cardone, Geraldine M. O'Connor, Cuiyan Tan, Hongchuan Li, Stephen K. Anderson, Simon A. Jones, Weigo Zhang, Philip R. Taylor, Giorgio Trinchieri, and Daniel W. McVicar
Loss of Function of the Mouse Sharpin Gene Results in Peyer’s Patch Regression., Rosemarie Seymour, Bobbi-Jo Shirley, Harm HogenEsch, Leonard D. Shultz, and John P. Sundberg
Submissions from 2012
Zwitterionic Chitosan Derivative, a New Biocompatible Pharmaceutical Excipient, Prevents Endotoxin-Mediated Cytokine Release, Gaurav Bajaj, William G. Van Alstine, and Yoon Yeo
Mycoplasma haemocanis – the canine hemoplasma and its feline counterpart in the genomic era, Naila C. do Nascimento, Andrea P. Santos, Ana MS Guimaraes, Phillip J. SanMiguesl, and Joanne Messick
Heat or Insulation: Behavioral Titration of Mouse Preference for Warmth or Access to a Nest., Brianna N. Gaskill, Christopher J. Gordon, Edmond A. Pajor, Jeffrey R. Lucas, Jerry K. Davis, and Joseph P. Garner
Impact of Preexisting Adenovirus Vector Immunity on Immunogenicity and Protection Conferred with an Adenovirus-Based H5N1 Influenza Vaccine, Aseem Pandey, Neetu Singh, Sai V. Vemula, Laurent Couetil, Jacqueline M. Katz, Ruben Donis, Suryaprakash Sambhara, and Suresh K. Mittal
The effect of infection order of porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus on dually infected swine alveolar macrophages, Yi-Chieh Tsai, Hui-Wen Chang, Chian-Ren Jeng, Tsang L. Lin, Chun-Ming Lin, Cho-Hua Wan, and Victor Fei Pang
Optimal Population of FoxP3+ T Cells in Tumors Requires an Antigen Priming-Dependent Trafficking Receptor Switch., Chuanwu Wang, Jee H. Lee, and Chang H. Kim
SHARPIN Is Essential for Cytokine Production, NF-κB Signaling, and Induction of Th1 Differentiation by Dendritic Cells, Zhe Wang, Anna Sokolovska, Rosemarie Seymour, John P. Sundberg, and Harm HogenEsch
Submissions from 2011
Complete Genome Sequence of Mycoplasma suis and Insights into Its Biology and Adaption to an Erythrocyte Niche, Ana MS Guimaraes, Andrea P. Santos, Phillip SanMiguel, Thomas Walter, Jorge Timenetsky, and Joanne Messick
Formulation of a Killed Whole Cell Pneumococcus Vaccine - Effect of Aluminum Adjuvants on the Antibody and IL-17 Response., Harm HogenEsch, Anisa Dunham, Bethany Hansen, Kathleen Anderson, Jean-Francois Maisonneuve, and Stanley L. Hem
Differential Effects of Peptidoglycan Recognition Proteins on Experimental Atopic and Contact Dermatitis Mediated by Treg and Th17 Cells., Sin Yong Park, Dipika Gupta, Chang H. Kim, and Roman Dziarski
Comparison of genomic and proteomic data in recurrent airway obstruction affected horses using ingenuity pathway analysis, Julien Racine, Vinzenz Gerber, Marybeth Miskovic Feutz, C Paige Riley, Jiri Adamec, June E. Swinburne, and Laurent Couetil
Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence, Andrea P. Santos, Ana MS Guimaraes, Naila C. do Nascimento, Phillip J. SanMiguel, Samuel W. Martin, and Joanne Messick
Phenotype, Effector Function, and Tissue Localization of PD-1-Expressing Human Follicular Helper T Cell Subsets, Chuanwu Wang, Peter Hillsamer, and Chang H. Kim
Submissions from 2010
Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions, Giovanni P. Burrai, Sulma Mohammed, Margaret A. Miller, Vincenzo Marras, Salvatore Pirino, Maria F. Addis, Sergio Uzzau, and Elisabetta Antuofermo
Spontaneous Feline Mammary Intraepithelial Lesions as a Model for Human Estrogen Receptor- and Progesterone Receptor-Negative Breast Lesions., Giovanni P. Burrai, Sulma Mohammed, Margaret A. Miller, Vincenzo Marras, Salvatore Pirino, Maria F. Addis, Sergio Uzzau, and Elisabetta Antuofermo
Identification of a Single-Nucleotide Insertion in the Promoter Region Affecting the sodC Promoter Activity in Brucella neotomae, Dina A. Moustafa, Neeta Jain, Nammalwar Sriranganathan, and Ramesh Vemulapalli
Submissions from 2009
A Time Series Model of the Occurrence of Gastric Dilatation-Volvulus in a Population of Dogs, Michael Levine and George E. Moore
Submissions from 2008
Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-α in endobronchial biopsies in horses with recurrent airway obstruction, Miia Riihimaki, Amanda Raine, Jamshid Pourazar, Thomas Sandstrom, Tatiana Art, Pierre Lekeux, Laurent Couetil, and John Pringle
Submissions from 2005
Human CD57+ Germinal Center-T Cells are the Major Helpers for GC-B Cells and Induce Class Switch Recombination, Jong R. Kim, Hyung W. Lim, Seung G. Kang, Peter Hillsamer, and Chang H. Kim