The attenuation coefficient and the speed of 10 MHz ultrasound were determined in canine blood at 37 oC by a differential path length technique. Blood specimens with packed cell volumes (PCV) ranging from 0 to 53% were prepared by separating the cells from the plasma and mixing the two components. The mean attenuation coefficient increased linearly with packed cell volume, the least squares regression function being (dB/cm) = 0.992 +0.039 PCV with a standard error of the estimate = 0.255. The speed of 10 MHz ultrasound, c, in millimetres per second, increased with packed cell volume, the regression function for a wave equation model being 1/C2 = 0.418 +2.09 10-4 (PCV) 1.75 105 (PCV)2 with a standard error of the estimate = 0.0049 (mm/s)2. Both the attention coefficient and speed of 10 MHz ultrasound were greater in blood than in plasma to a degree dependent on the packed cell volume.
Attenuation coefficient, Blood, Packed cell volume, Ultrasound
Date of this Version
Hughes, D J.; Geddes, L A.; Babbs, Charles F.; Bourland, J D.; and Newhouse, V L., "Attenuation and speed of 10 MHz ultrasound in canine blood of various packed cell volumes at 37C" (1979). Weldon School of Biomedical Engineering Faculty Publications. Paper 79.