Regional Blood Flow during Cardiopulmonary Resuscitation with Abdominal Counterpulsation in Dogs
The addition of abdominal counterpulsation to standard cardiopulmonary resuscitation (IAC-CPR) during ventricular fibrillation has been shown to improve cardiac output, oxygen uptake, and central arterial blood pressure in dogs. The present study was performed to determine the effect of IAC-CPR on regional blood flow. Regional blood flow was measured with radioactively labeled microspheres during sinus rhythm and during alternate periods of IAC-CPR and standard CPR (STD-CPR) in nine dogs anesthetized with pentobarbital. Blood pressures and oxygen uptake were measured continuously. As in previous studies, diastolic arterial pressure was higher (30.8%) during IAC-CPR than during STD-CPR, as were cardiac output (24.5%) and oxygen uptake (37.5%). Whole brain and myocardial blood flow increased 12.0% and 22.7%, respectively, during IAC-CPR. Blood flow to abdominal organs was not changed appreciably in response to abdominal compression, and postmortem examination revealed no gross trauma to the abdominal viscera. The IAC-CPR technique is simple and is easily added to present basic life support procedures. In light of the improvements observed in myocardial and cerebral blood flow, IAC-CPR could significantly improve the outcome of CPR attempts.
abdomen, brain, heart, hemodynamics, IAC-CPR, perfusion
Date of this Version
Voorhees, William D. III; Ralston, Sandra H.; and Babbs, Charles F., "Regional Blood Flow during Cardiopulmonary Resuscitation with Abdominal Counterpulsation in Dogs" (1984). Weldon School of Biomedical Engineering Faculty Publications. Paper 116.
This is the author accepted manuscript version of Voorhees W.D., Ralston S.H., Babbs C.F., Regional blood flow during CPR with abdominal counterpulsation in dogs, Amer J Emergency Medicine 2, 123-128, 1984. Copyright Elsevier, it is made available here CC-BY-NC-ND, and the version of record is available at https://doi.org/10.1016/S0735-6757(84)80003-0.