SERS aptasensor from nanorod-nanoparticle junction for protein detection

Yuling Wang, Purdue University - Main Campus
Kyuwan Lee, Purdue University - Main Campus
Joseph Irudayaraj, Purdue University - Main Campus

Date of this Version

2010

Citation

DOI: 10.1039/b919607b

This document has been peer-reviewed.

 

Abstract

A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.

Discipline(s)

Engineering | Nanoscience and Nanotechnology

 

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