Thin layer chromatography using silica colloidal crystals for the separation of proteins
Abstract
Protein separation is a growing field of broad interest in biological and medical research with current implications in drug development and disease detection. To this end, thin layer chromatography is an attractive method due to its simplicity and versatility. The research presented herein details a study to demonstrate the potential viability of this technique in enabling separation and detection of unlabelled protein samples. As a proof of concept, clear separation was achieved between bovine serum albumin and both insulin and carbonic anhydrase using sintered channels containing silica colloidal crystal.
Degree
M.S.
Advisors
Wirth, Purdue University.
Subject Area
Inorganic chemistry
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