An implantable intraocular pressure monitoring device
Abstract
Glaucoma is the second leading cause of blindness, and the number of people diagnosed is expected to increase approximately 30% from 60 million cases to 79 million worldwide over the next 10 years. While there are many risk factors associated with glaucoma, the leading diagnostic tool for glaucomatous detection still remains intraocular pressure (IOP). The gold standard for monitoring IOP, Goldmann tonometry, uses mathematical calculations to determine pressure based on deflection of the cornea, but this method can still give inaccurate results based on a patient's anatomy. To obtain an accurate diagnosis, trending is a necessary component that is often overlooked since a patient is seen rarely over the course of a year. Therefore there is a need for a device that can continuously monitor IOP and give an ophthalmologist better tools for diagnosing and monitoring IOP. The work presented describes the design, integration, and implementation of a continuous monitoring IOP device. An understanding of powering both by inductive coupling as well as radio frequency powering is discussed, leading into the development of an IOP device. Ex-vivo bench top testing is conducted on powering, measurement, and transmission of the IOP device. Finally, an in-vivo analysis of a completed device is conducted using a rabbit animal model.
Degree
Ph.D.
Advisors
Irazoqui, Purdue University.
Subject Area
Ophthalmology|Biomedical engineering
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