The Department of Comparative Pathobiology at Purdue University provides knowledge in disease phenomena basic to all species including humans, at the molecular, cellular, organismal and ecosystem level. Faculty, staff, and students are involved in research and learning in a variety of areas including pathobiology, infectious diseases and vaccines, cancer biology, nanomedicine, toxicology, disease surveillance and human-animal interactions.

This series contains publications from the Department of Comparative Pathobiology at Purdue University.

Follow

Submissions from 2016

PDF

In vitro antibacterial activity of rhodanine derivatives against pathogenic clinical isolates, Ahmed Abdelkhalek, Charles R. Ashby Jr., Bhargav A. Patel, Tanaji T. Talele, and Mohamed Naguieb Seleem

PDF

Ureaplasma diversum Genome Provides New Insights about the Interaction of the Surface Molecules of This Bacterium with the Host, Lucas M. Marques, Izadora S. Rezende, Maysa S. Barbosa, Ana M. Guimarães, Hellen B. Martins, Guilherme B. Campos, Naila C. do Nascimento, Andrea P. dos Santos, Aline T. Amorim, Verena M. Santos, Sávio T. Farias, Fernanda A C Carrence, Lauro M. de Souza, Melissa Buzinhani, Victor E. Arana-Chavez, Maria E. Zenteno, Gustavo P. Amarante-Mendes, Joanne Messick, and Jorge Timenetsky

Submissions from 2015

PDF

Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine, Tiebing Liang, Mouhamad Alloosh, Lauren N. Bell, Allison Fullenkamp, Romil Saxena, William G. Van Alstine, Phelan Bybee, Klára Werling, Michael Sturek, Naga Chalasani, and Howard C. Masuoka

PDF

Antibacterial evaluation of synthetic thiazole compounds in vitro and in vivo in a methicillin-resistant staphylococcus aureus (MRSA) skin infection mouse model, Haroon Mohammad, Mark A. Cushman, and Mohamed Naguieb Seleem

PDF

Antibacterial Characterization of Novel Synthetic Thiazole Compounds against Methicillin-Resistant Staphylococcus pseudintermedius, Haroon Mohammad, P.V. N. Reddy, Dennis Monteleone, Abdelrahman S. Mayhoub, Mark S. Cushman, G. Kenitra Hammac, and Mohamed N. Seleem

PDF

Repurposing Celecoxib as a Topical Antimicrobial Agent, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem

PDF

Repurposing clinical molecule ebselen to combat drug resistant pathogens, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem

PDF

Repurposing ebselen for Treatment of Multidrug-Resistant Staphylococcal Infections, Shankar Thangamani, Waleed Younis, and Mohamed N. Seleem

Submissions from 2013

PDF

Energy Reallocation to Breeding Performance through Improved Nest Building in Laboratory Mice., Brianna N. Gaskill, Kathleen R. Pritchett-Corning, Christopher J. Gordon, Edmond A. Pajor, Jeffrey R. Lucas, Jerry K. Davis, and Joseph P. Garner

PDF

Social Behaviors Increase in Children with Autism in the Presence of Animals Compared to Toys., Marguerite E. O'Haire, Samantha J. McKenzie, Alan M. Beck, and Virginia Slughter

PDF

LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells., Selinda J. Orr, Ashley R. Burg, Tim Chan, Laura Quigley, Gareth W. Jones, Jill W. Ford, Deborah Hodge, Catherine Razzook, Joseph Sarhan, Yava L. Jones-Hall, Gillian C. Whittaker, Kimberly C. Boelte, Lyudmila Lyakh, Marco Cardone, Geraldine M. O'Connor, Cuiyan Tan, Hongchuan Li, Stephen K. Anderson, Simon A. Jones, Weigo Zhang, Philip R. Taylor, Giorgio Trinchieri, and Daniel W. McVicar

PDF

Loss of Function of the Mouse Sharpin Gene Results in Peyer’s Patch Regression., Rosemarie Seymour, Bobbi-Jo Shirley, Harm HogenEsch, Leonard D. Shultz, and John P. Sundberg

Submissions from 2012

PDF

Zwitterionic Chitosan Derivative, a New Biocompatible Pharmaceutical Excipient, Prevents Endotoxin-Mediated Cytokine Release, Gaurav Bajaj, William G. Van Alstine, and Yoon Yeo

PDF

Mycoplasma haemocanis – the canine hemoplasma and its feline counterpart in the genomic era, Naila C. do Nascimento, Andrea P. Santos, Ana MS Guimaraes, Phillip J. SanMiguesl, and Joanne Messick

PDF

Heat or Insulation: Behavioral Titration of Mouse Preference for Warmth or Access to a Nest., Brianna N. Gaskill, Christopher J. Gordon, Edmond A. Pajor, Jeffrey R. Lucas, Jerry K. Davis, and Joseph P. Garner

PDF

Impact of Preexisting Adenovirus Vector Immunity on Immunogenicity and Protection Conferred with an Adenovirus-Based H5N1 Influenza Vaccine, Aseem Pandey, Neetu Singh, Sai V. Vemula, Laurent Couetil, Jacqueline M. Katz, Ruben Donis, Suryaprakash Sambhara, and Suresh K. Mittal

PDF

The effect of infection order of porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus on dually infected swine alveolar macrophages, Yi-Chieh Tsai, Hui-Wen Chang, Chian-Ren Jeng, Tsang L. Lin, Chun-Ming Lin, Cho-Hua Wan, and Victor Fei Pang

PDF

Optimal Population of FoxP3+ T Cells in Tumors Requires an Antigen Priming-Dependent Trafficking Receptor Switch., Chuanwu Wang, Jee H. Lee, and Chang H. Kim

PDF

SHARPIN Is Essential for Cytokine Production, NF-κB Signaling, and Induction of Th1 Differentiation by Dendritic Cells, Zhe Wang, Anna Sokolovska, Rosemarie Seymour, John P. Sundberg, and Harm HogenEsch

Submissions from 2011

PDF

Complete Genome Sequence of Mycoplasma suis and Insights into Its Biology and Adaption to an Erythrocyte Niche, Ana MS Guimaraes, Andrea P. Santos, Phillip SanMiguel, Thomas Walter, Jorge Timenetsky, and Joanne Messick

PDF

Formulation of a Killed Whole Cell Pneumococcus Vaccine - Effect of Aluminum Adjuvants on the Antibody and IL-17 Response., Harm HogenEsch, Anisa Dunham, Bethany Hansen, Kathleen Anderson, Jean-Francois Maisonneuve, and Stanley L. Hem

PDF

Differential Effects of Peptidoglycan Recognition Proteins on Experimental Atopic and Contact Dermatitis Mediated by Treg and Th17 Cells., Sin Yong Park, Dipika Gupta, Chang H. Kim, and Roman Dziarski

PDF

Comparison of genomic and proteomic data in recurrent airway obstruction affected horses using ingenuity pathway analysis, Julien Racine, Vinzenz Gerber, Marybeth Miskovic Feutz, C Paige Riley, Jiri Adamec, June E. Swinburne, and Laurent Couetil

PDF

Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence, Andrea P. Santos, Ana MS Guimaraes, Naila C. do Nascimento, Phillip J. SanMiguel, Samuel W. Martin, and Joanne Messick

PDF

Phenotype, Effector Function, and Tissue Localization of PD-1-Expressing Human Follicular Helper T Cell Subsets, Chuanwu Wang, Peter Hillsamer, and Chang H. Kim

Submissions from 2010

PDF

Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions, Giovanni P. Burrai, Sulma Mohammed, Margaret A. Miller, Vincenzo Marras, Salvatore Pirino, Maria F. Addis, Sergio Uzzau, and Elisabetta Antuofermo

PDF

Spontaneous Feline Mammary Intraepithelial Lesions as a Model for Human Estrogen Receptor- and Progesterone Receptor-Negative Breast Lesions., Giovanni P. Burrai, Sulma Mohammed, Margaret A. Miller, Vincenzo Marras, Salvatore Pirino, Maria F. Addis, Sergio Uzzau, and Elisabetta Antuofermo

PDF

Identification of a Single-Nucleotide Insertion in the Promoter Region Affecting the sodC Promoter Activity in Brucella neotomae, Dina A. Moustafa, Neeta Jain, Nammalwar Sriranganathan, and Ramesh Vemulapalli

Submissions from 2009

PDF

A Time Series Model of the Occurrence of Gastric Dilatation-Volvulus in a Population of Dogs, Michael Levine and George E. Moore

Submissions from 2008

PDF

Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-α in endobronchial biopsies in horses with recurrent airway obstruction, Miia Riihimaki, Amanda Raine, Jamshid Pourazar, Thomas Sandstrom, Tatiana Art, Pierre Lekeux, Laurent Couetil, and John Pringle

Submissions from 2005

PDF

Human CD57+ Germinal Center-T Cells are the Major Helpers for GC-B Cells and Induce Class Switch Recombination, Jong R. Kim, Hyung W. Lim, Seung G. Kang, Peter Hillsamer, and Chang H. Kim